Fitting a square peg into a round hole: simulating a modulated protein crystal

A square peg in a round hole.

My fear is that the hopes that I have for my practice, and the beliefs I have come to hold regarding how I would like to teach will be worn down by the myriad realities and pressures I am likely to experience as a beginning teacher. In many ways I suspect that the teaching tools with which I have been equipped by my pre-service training, based largely on constructivist principles, may ill-prepa...

Square peg in a round hole.

Fitting a Round Peg in a Square Hole: Japanese Resource Grammar in GF

Brain not processing: is finding a role for BNP in sepsis like fitting a square peg into a round hole?

Since its introduction to the intensive care setting a decade ago, B-type natriuretic peptide has been the focus of studies in different areas (in particular, sepsis). With this biomarker, as with many newly identified biomarkers, its diagnostic performance was pursued initially and then its ability to predict outcomes. Despite all the efforts, results have not been consistent and the applicati...

Fitting a square peg into a round hole: are the current Surviving Sepsis Campaign guidelines feasible for Africa?

In their article, Baelani and colleagues surveyed anesthesia providers from African low- and middle-income countries (LMICs) to evaluate whether or not the current Surviving Sepsis Campaign (SSC) guidelines are feasible in such resource-constrained settings. The authors report that an alarmingly low percentage of hospitals have the capacity to implement the SSC guidelines in their entirety but ...